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. 2013 Nov 1;3(11):e156. doi: 10.1038/bcj.2013.53

Figure 6.

Figure 6

Plasma cell transcription signatures in cMYC/KRAS12V-transduced plasmacytoma cells. (a) Expression of selected genes from microarray results were confirmed using quantitative real-time PCR. All data represent mean of triplicate experiments. (b) GSEA showed a plasma cell gene expression signature of plasmacytoma cells. (c) GSEA showed genes associated with B-cell receptor signaling to be significantly downregulated in plasmacytoma cells. (d) GSEA showed genes in IRF4 target gene set were upregulated in plasmacytoma cells. (e) Table of the gene sets related to plasma cell differentiation and survival.