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. 2013 Nov 1;3(11):e156. doi: 10.1038/bcj.2013.53

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Copyright © 2013 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Gene expression signatures of cMYC/KRAS12V-transduced plasmacytoma cells. (a) Using GSEA, four gene sets associated with MYC activation are presented in plasmacytoma cells compared with IgM⁺ B cells. (b) GSEA showed genes upregulated by mTOR in plasmacytoma cells. (c) GSEA showed that genes regulating cell cycle are significantly enriched in plasmacytoma cells. (d) Table of gene sets of MYC, mTOR, cell cycle and cancer-related pathways (from top to bottom) in cMYC/KRAS12V-transduced plasmacytoma cells.