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Effects of oridonin and the selected dienone analogues on normal human mammary epithelial cell (HMEC) proliferation.
| Compounds | IC50 (μM)a |
|---|---|
| 1 | 5.60 ± 0.38 |
| 6 | 5.11 ± 0.18 |
| 7 | 4.95 ± 0.63 |
| 10 | 4.51 ± 0.54 |
| 19 | 10.2 ± 0.24 |
| 20 | 10.1 ± 0.68 |
Cell line: HMEC. Software: MasterPlex ReaderFit 2010, MiraiBio, Inc. Values are mean ± SE of three independent experiments.
