Table 2.

For each significant cluster, peak voxel MNI coordinates (x, y, z), t-statistic and p-value, and cluster size(k) are listed separately for each voxel-wise analysis.

Brain Region	x	y	z	k	t	p
WMH increase with age (Figure 2)
R posterior thalamic radiation	33	−54	19	71551	8.13	<0.0001
WMH increase with lower Speed and Flexibility factor score (Figure 4a)
R superior corona radiata	26	14	25	43,869	6.67	<0.0001
R middle occipital WM	27	−84	4	325	4.57	<0.0001
Body of the corpus callosum	−6	−22	22	296	4.38	<0.0001
L medial frontal WM	−12	−21	58	90	4.35	<0.0001
WMH increase with lower Speed and Flexibility factor score independent of age (Figure 4b)
L superior corona radiata	−27	5	34	1,838	4.97	<0.0001
R superior corona radiata	28	17	28	726	4.87	<0.0001