Table 2.

Reaction Scope with Respect to Phenols^a

entry	phenol	product	yield, %
1	4-tBu-phenol		88 73b
2	4-SMe-phenol		75
3	3-CF3-phenol		55
4	4-Br-phenol		78
5	3-I-phenol		56
6	3-CO2Me-phenol		84
7	3-Cl-4-Me-phenol		77
8	2-Cl-4-MeO-phenol		78
9c	3-amino-phenol		57

^aScale: 0.5 mmol; time: 2–8 h; 1/1 amide/phenol ratio, 110 °C, 11% catalyst = 22 mol % Cu. Please see Supporting Information for details.

^bScale: 3.2 mmol, 5.5 mol % (CuOH)₂CO₃.

^cAmide/phenol ratio: 1/2.