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. Author manuscript; available in PMC: 2014 Jul 11.
Published in final edited form as: J Med Chem. 2013 Jun 20;56(13):10.1021/jm400405z. doi: 10.1021/jm400405z

Table 6.

Antiviral activity of catechol-containing thienopyrimidinones. sr, selectivity ratio, i.e., CC50/EC50.

Compound EC50 (μM) CC50 (μM) sr
9 3.8 8.9 2.3
24 1.9 11.2 5.9
25 7.9 25.4 3.2
26 9.2 33.7 3.7
29 1.6 6.8 4.3
31 3.1 12.4 4.0
32 2.7 9.8 3.6