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. 2013 Dec 21;35(6):907–913. doi: 10.1155/2013/796290

Table 2.

Genotype and allele frequencies of TP53 signaling pathway gene polymorphisms.

Fertile n (%) Endometriosis n (%) P value* IVF Failure n (%) P value**
MDM2
rs2279744
 TT 57 (42.5) 41 (41.8) 0.824 48 (41.7) 0.918
 TG 64 (47.8) 45 (45.9) 54 (47)
 GG 13 (9.7) 12 (12.2) 13 (11.3)
 G 0.67 0.65 0.765 0.65 0.765
 T 0.33 0.35 0.35
MDM4
rs1563828
 CC 34 (25.4) 34 (34.7) 0.268 40 (34.8) 0.141
 CT 71 (53) 43 (42.9) 59 (51.3)
 TT 29 (21.6) 21 (21.4) 16 (13.9)
 C 0.52 0.57 0.477 0.6 0.254
 T 0.48 0.43 0.4
HAUSP
rs1529916
 CC 73 (54.5) 53 (54.1) 0.977 53 (46.1) 0.224
 CT 52 (38.8) 39 (39.8) 48 (41.7)
 TT 9 (6.7) 6 (6.1) 14 (12.2)
 C 0.74 0.74 1 0.67 0.277
 T 0.26 0.26 0.33
LIF
rs929271
 TT 57 (42.5) 47 (48) 0.702 46 (40) 0.784
 TG 60 (44.8) 39 (39.8) 51 (44.3)
 GG 17 (12.7) 12 (12.2) 18 (15.7)
 T 0.65 0.68 0.653 0.62 0.659
 G 0.35 0.32 0.38
ESR1
rs9340799
 AA 71 (53) 27 (27.6) <0.001 45 (39.1) 0.018
 AG 54 (40.3) 55 (56.1) 51 (44.3)
 GG 9 (6.7) 16 (16.3) 19 (16.5)
 A 0.73 0.55 0.008 0.61 0.071
 G 0.27 0.45 0.39
ESR1
rs2234693
 CC 27 (20.1) 18 (18.4) 0.861 17 (14.8) 0.105
 CT 69 (51.5) 54 (55.1) 51 (44.3)
 TT 38 (28.4) 26 (26.5) 47 (40.9)
 C 0.46 0.46 1 0.37 0.196
 T 0.54 0.54 0.63

*Chi-square analysis for the difference between Fertile and Endometriosis groups. **Chi-square analysis for the difference between Fertile and IVF Failure groups.