Table 2.

Precompression parameters of designed formulations (F1–F17).

Formulation code	Precompression evaluation parameters
	Bulk density (mg/mL)	Tapped density (mg/mL)	Carr's index	Angle of repose	Hausner's ratio
	(n = 3) Mean ± SD	(n = 3) Mean ± SD	(%)	(n = 3) Mean ± SD
F1	0.384 ± 0.009	0.5 ± 0.010	23.08	23.01 ± 1.289	1.13
F2	0.4081 ± 0.007	0.5 ± 0.012	18.38	27.02 ± 1.30	1.22
F3	0.4545 ± 0.006	0.52631 ± 0.014	13.64	22.29 ± 0.912	1.55
F4	0.4166 ± 0.010	0.52631 ± 0.011	15.56	28.36 ± 1.344	1.18
F5	0.4233 ± 0.004	0.4825 ± 0.013	12.4	28.1 ± 1.23	1.14
F6	0.4324 ± 0.009	0.5059 ± 0.008	15.7	28.1 ± 1.45	1.17
F7	0.4256 ± 0.008	0.4809 ± 0.015	12.8	27.6 ± 0.82	1.13
F8	0.4065 ± 0.011	0.4837 ± 0.011	15.9	29.32 ± 1.23	1.19
F9	0.4324 ± 0.009	0.4886 ± 0.009	12.8	27.6 ± 1.66	1.13
F10	0.4065 ± 0.007	0.4837 ± 0.012	12.3	29.36 ± 1.25	1.19
F11	0.4546 ± 0.006	0.5227 ± 0.014	11.2	28.76 ± 1.33	1.15
F12	0.4166 ± 0.009	0.4915 ± 0.012	11.3	26.74 ± 0.911	1.18
F13	0.4324 ± 0.011	0.48861 ± 0.009	12.2	25.3 ± 1.155	1.13
F14	0.4088 ± 0.006	0.4782 ± 0.010	11.5	28.7 ± 0.81	1.17
F15	0.4632 ± 0.005	0.528 ± 0.011	14.7	28 ± 1.43	1.14
F16	0.4321 ± 0.009	0.4882 ± 0.012	15.7	29.2 ± 1.234	1.13
F17	0.4776 ± 0.007	0.5667 ± 0.014	16.9	28.67 ± 1.33	1.14
F18	0.486 ± 0.005	0.523 ± 0.012	11.5	27.34 ± 1.55	1.13