Table 3.
Correlation matrix for elliptic erythrocyte shape, oxidative stress markers, and β-actin erythrocyte membrane content.
| Elliptocytes | 4-HNE PAs | IE-NPBI | F2-IsoPs | β-Actin content | 4-HNE β-Actin adducts |
|
|---|---|---|---|---|---|---|
| Elliptocytes | 0.779 [0.630–0.873] P < 0.0001 |
0.334 [0.045–0.572] P = 0.00246 |
0.588 [0.356–0.752] P < 0.0001 |
−0.860 [−0.921 to −0.758] P < 0.0001 |
0.887 [0.803–0.937] P < 0.0001 |
|
| 4-HNE PAs | 0.397 [0.117–0.618] P = 0.0068 |
0.774 [0.622–0.869] P < 0.0001 |
−0.886 [−0.936 to −0.801] P < 0.0001 |
0.889 [0.806–0.938] P < 0.0001 |
||
| IE-NPBI | 0.415 [0.139–0.632] P = 0.0045 |
−0.414 [−0.631 to –0.138] P = 0.0046 |
0.340 [0.052–0.576] P = 0.0223 |
|||
| F2-IsoPs | −0.628 [−0.778 to −0.410] P < 0.0001 |
0.579 [0.344–0.746] P < 0.0001 |
||||
| β-Actin content | −0.960 [−0.978 to –0.929] P < 0.0001 |
|||||
| 4-HNE β-Actin Adducts |
Data are Spearman's rho correlation coefficients (in square brackets are the 95% confidence intervals for regression).
IE-NPBI: intraerythrocyte nonprotein-bound-iron; F2-IsoPs: F2-isoprostanes; 4-HNE Pas: 4-HNE protein adducts.