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EAE in wild-type and SAP-Tg mice
| Mouse genotype | Incidence | Day of onset (mean ± s.d.) | Maximum clinical score (mean ± s.d.) |
|---|---|---|---|
|
| |||
| Wild type | 15 out of 15 (100%) | 14.08 (±2.33) | 2.95 (±0.68) |
| SAP-Tg | 12 out of 15 (80%) | 14.91 (±2.43) | 1.71 (±0.34)* |
Abbreviations: EAE, experimental autoimmune encephalomyelitis; SAP, serum amyloid P component; Tg, transgenic. Results are cumulative data from three different experiments, * p<0.05, as compared with corresponding wild-type controls.
