Table 1.

Other selected predicted conserved targets of miR-33a/b involved in lipid homeostasis.

Target gene	Gene name	# sites	Target scan	PICTAR	miRanda	targeted in
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	3	x	x	x	Hsa, Ptr, Mmu, Rno, Cfa, Mdo, Oan, Gga, Xtr
CROT	Carnitine O-octanoyltransferase	2	x	(x)	x	Hsa, Ptr, Mmu, Rno, Fca, Aca, Gga
MRPS25	Mitochondrial ribosomal protein S25	2	x	x	x	Hsa, Ptr, Mmu, Rno, Cfa, Mdo, Oan, Gga
NPC1	Niemann-Pick disease, type C1	2	x		x	Hsa, Ptr, Mmu, Rno, Cfa, Gga
SIRT6	Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)	1	x		x	Hsa, Ptr, Mmu, Cfa
PRKAA1	Protein kinase, AMP-activated, alpha 1 catalytic subunit	2	x	x	x	Hsa, Ptr, Mmu, Rno, Cfa, Mdo, Gga, Xtr
HADHB	Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	1	x	x	x	Hsa, Ptr, Mmu, Rno, Cfa, Mdo, Oan, Gga
SNF1LK	SNF1-like kinase	1	x	x	x	Hsa, Ptr, Mdo, Oan, Gga
IRS-2	Insulin receptor substrate 2	1	x	x	x	Hsa, Ptr, Mmu, Rno, Cfa, Mdo, Oan
HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	1	x		x	Hsa, Ptr, Mmu, Oan
CS	Citrate synthase	1	x		x	Hsa, Ptr, Cfa, Oan, Xtr
CPT1A	Carnitine palmitoyltransferase 1A (liver)	1			x	Hsa, Mmu, Rno, Cfa, Gga, Dme

Selected conserved miR-33a/b targets involved in cholesterol/lipid and energy homeostasis as predicted by TargetScan (Grimson et al. 2007), PICTAR, and miRanda.

Hsa = human; Ptr = chimpanzee; Mmu = mouse; Rno = rat; Cfa = dog; Fca = Cat; Mdo = opossum; Oan = platypus; Gga = chicken Xtr = frog; Dme = fruitfly