Table 2.
Between eye symmetry of pupillary light reflex measured by pupillography in patients with glaucoma (N=148) and controls (N=71)
| Correlation coefficient | Absolute between-eye score Mean ± SD | |||
|---|---|---|---|---|
| Glaucoma | Control | Glaucoma | Control | |
| White, Full field, Bright | ||||
| Amplitude* | 0.76 | 0.96 | 0.47 ± 0.51 | 0.14 ± 0.10 |
| Latency* | 0.83 | 0.93 | 0.23 ± 0.21 | 0.15 ± 0.14 |
| Max constriction velocity* | 0.89 | 0.98 | 0.36 ± 0.36 | 0.12 ± 0.11 |
| Time to max constriction velocity* | 0.86 | 0.92 | 0.16 ± 0.13 | 0.11 ± 0.08 |
| Max dilation velocity | 0.76 | 0.77 | 0.42 ± 0.53 | 0.30 ± 0.49 |
| Time to max dilation velocity* | 0.74 | 0.88 | 0.24 ± 0.19 | 0.12 ± 0.11 |
| Red, Full field, Bright | ||||
| Amplitude* | 0.66 | 0.91 | 0.68 ± 0.72 | 0.28 ± 0.25 |
| Latency | 0.73 | 0.85 | 0.31 ± 0.26 | 0.25 ± 0.23 |
| Max constriction velocity* | 0.79 | 0.90 | 0.50 ± 0.50 | 0.36 ± 0.28 |
| Time to max constriction velocity* | 0.80 | 0.81 | 0.23 ± 0.23 | 0.17 ± 0.13 |
| Max dilation velocity | 0.73 | 0.83 | 0.55 ± 0.49 | 0.47 ± 0.52 |
| Time to max dilation velocity* | 0.65 | 0.74 | 0.30 ± 0.25 | 0.20 ± 0.19 |
| Green, Full field, Bright | ||||
| Amplitude* | 0.74 | 0.94 | 0.57 ± 0.57 | 0.22 ± 0.19 |
| Latency | 0.82 | 0.87 | 0.24 ± 0.25 | 0.24 ± 0.20 |
| Max constriction velocity* | 0.83 | 0.96 | 0.49 ± 0.44 | 0.21 ± 0.18 |
| Time to max constriction velocity | 0.73 | 0.79 | 0.22 ± 0.20 | 0.19 ± 0.14 |
| Max dilation velocity | 0.66 | 0.48 | 0.55 ± 0.63 | 0.51 ± 0.68 |
| Time to max dilation velocity | 0.66 | 0.59 | 0.29 ± 0.24 | 0.25 ± 0.20 |
| Blue, Full field, Bright | ||||
| Amplitude* | 0.76 | 0.92 | 0.60 ± 0.58 | 0.28 ± 0.20 |
| Latency* | 0.74 | 0.92 | 0.33 ± 0.27 | 0.18 ± 0.14 |
| Max constriction velocity* | 0.84 | 0.92 | 0.45 ± 0.43 | 0.33 ± 0.23 |
| Time to max constriction velocity | 0.77 | 0.77 | 0.23 ± 0.22 | 0.19 ± 0.15 |
| Max dilation velocity | 0.68 | 0.69 | 0.59 ± 0.64 | 0.46 ± 0.52 |
| Time to max dilation velocity* | 0.61 | 0.68 | 0.34 ± 0.24 | 0.22 ± 0.19 |
| Yellow, Full Field, Bright | ||||
| Amplitude* | 0.75 | 0.93 | 0.59 ± 0.55 | 0.23 ± 0.19 |
| Latency* | 0.85 | 0.91 | 0.27 ± 0.19 | 0.20 ± 0.17 |
| Max constriction velocity* | 0.86 | 0.96 | 0.46 ± 0.41 | 0.23 ± 0.17 |
| Time to max constriction velocity* | 0.66 | 0.86 | 0.25 ± 0.24 | 0.16 ± 0.15 |
| Max dilation velocity | 0.75 | 0.79 | 0.48 ± 0.57 | 0.40 ± 0.42 |
| Time to max dilation velocity* | 0.60 | 0.69 | 0.31 ± 0.25 | 0.23 ± 0.21 |
| White, Peripheral, Bright | ||||
| Amplitude* | 0.62 | 0.85 | 0.81 ± 0.63 | 0.46 ± 0.33 |
| Latency* | 0.61 | 0.75 | 0.41 ± 0.36 | 0.27 ± 0.26 |
| Max constriction velocity* | 0.75 | 0.88 | 0.73 ± 0.53 | 0.47 ± 0.43 |
| Time to max constriction velocity* | 0.58 | 0.59 | 0.37 ± 0.29 | 0.28 ± 0.22 |
| Max dilation velocity* | 0.60 | 0.65 | 0.75 ± 0.78 | 0.52 ± 0.68 |
| Time to max dilation velocity | 0.57 | 0.43 | 0.32 ± 0.28 | 0.31 ± 0.24 |
| White, Peripheral, Dim | ||||
| Amplitude* | 0.68 | 0.75 | 0.77 ± 0.63 | 0.54 ± 0.45 |
| Latency | 0.61 | 0.75 | 0.45 ± 0.39 | 0.42 ± 0.31 |
| Max constriction velocity* | 0.78 | 0.85 | 0.71 ± 0.54 | 0.58 ± 0.49 |
| Time to max constriction velocity | 0.38 | 0.55 | 0.42 ± 0.43 | 0.33 ± 0.28 |
| Max dilation velocity | 0.48 | 0.39 | 0.71 ± 0.83 | 0.67 ± 0.85 |
| Time to max dilation velocity | 0.50 | 0.26 | 0.33 ± 0.30 | 0.28 ± 0.22 |
| White, Central, Bright | ||||
| Amplitude* | 0.54 | 0.57 | 1.52 ± 1.42 | 1.04 ± 0.80 |
| Latency | 0.35 | 0.32 | 0.73 ± 0.67 | 0.67 ± 0.60 |
| Max constriction velocity | 0.70 | 0.66 | 0.99 ± 0.98 | 0.78 ± 0.64 |
| Time to max constriction velocity | 0.27 | 0.49 | 0.54 ± 0.64 | 0.40 ± 0.32 |
| Max dilation velocity | 0.10 | 0.19 | 1.18 ± 1.53 | 1.30 ± 1.80 |
| Time to max dilation velocity | 0.40 | 0.26 | 0.51 ± 0.42 | 0.46 ± 0.38 |
| White, Central, Dim | ||||
| Amplitude* | 0.61 | 0.62 | 1.54 ± 1.72 | 1.00 ± 0.89 |
| Latency | 0.31 | 0.11 | 0.91 ± 0.81 | 0.88 ± 0.84 |
| Max constriction velocity | 0.70 | 0.75 | 1.02 ± 0.89 | 0.81 ± 0.64 |
| Time to max constriction velocity | 0.29 | 0.49 | 0.60 ± 1.16 | 0.45 ± 0.42 |
| Max dilation velocity | 0.42 | 0.46 | 0.93 ± 0.97 | 0.91 ± 0.84 |
| Time to max dilation velocity | 0.45 | 0.25 | 0.46 ± 0.35 | 0.50 ± 0.40 |
SD, standard deviation.
*
p-value<0.05 calculated with Student’s t-test.