Table 3.
Within-eye symmetry of pupil response to superonasal versus inferonasal stimulation measured by pupillography in patients with glaucoma (N=148) and controls (N=71).
| Correlation coefficient | Absolute within-eye score Mean ± SD | |||
|---|---|---|---|---|
| Glaucoma | Normal | Glaucoma | Normal | |
| White | ||||
| Amplitude* | 0.62 | 0.64 | 1.63 ± 1.23 | 1.20 ± 0.78 |
| Latency | 0.30 | 0.43 | 0.93 ± 0.70 | 0.78 ± 0.60 |
| Max constriction velocity | 0.72 | 0.70 | 1.17 ± 0.75 | 1.01 ± 0.56 |
| Time to max constriction velocity | 0.08 | 0.26 | 0.71 ± 0.96 | 0.51 ± 0.47 |
| Max dilation velocity | 0.13 | 0.52 | 1.29 ± 1.29 | 0.97 ± 0.72 |
| Time to max dilation velocity* | 0.26 | 0.24 | 0.54 ± 0.35 | 0.41± 0.26 |
| Red | ||||
| Amplitude* | 0.41 | 0.54 | 2.97 ± 2.48 | 2.28 ± 1.63 |
| Latency | 0.10 | 0.32 | 1.11 ± 0.80 | 0.99 ± 0.64 |
| Max constriction velocity* | 0.45 | 0.63 | 1.90 ± 1.39 | 1.47 ± 0.92 |
| Time to max constriction velocity | 0.22 | 0.39 | 0.72 ± 0.50 | 0.60 ± 0.39 |
| Max dilation velocity | 0.02 | 0.05 | 1.97 ± 1.50 | 2.19 ± 2.00 |
| Time to max dilation velocity | 0.07 | 0.08 | 0.82 ± 0.47 | 0.85 ± 0.52 |
| Green | ||||
| Amplitude* | 0.63 | 0.59 | 1.70 ± 1.14 | 1.31 ± 0.92 |
| Latency | 0.40 | 0.50 | 0.90 ± 0.63 | 0.78 ± 0.45 |
| Max constriction velocity | 0.73 | 0.69 | 1.18 ± 0.82 | 1.05 ± 0.66 |
| Time to max constriction velocity | 0.31 | 0.27 | 0.67 ± 0.86 | 0.53 ± 0.35 |
| Max dilation velocity | 0.07 | 0.05 | 1.57 ± 1.25 | 1.66 ± 1.69 |
| Time to max dilation velocity* | 0.26 | 0.07 | 0.61 ± 0.37 | 0.74 ± 0.42 |
| Blue | ||||
| Amplitude | 0.62 | 0.60 | 1.99 ± 1.91 | 1.51 ± 1.10 |
| Latency* | 0.20 | 0.53 | 0.98 ± 0.74 | 0.74 ± 0.46 |
| Max constriction velocity | 0.70 | 0.67 | 1.37 ± 1.05 | 1.16 ± 0.87 |
| Time to max constriction velocity* | 0.25 | 0.47 | 0.64 ± 0.48 | 0.50 ± 0.36 |
| Max dilation velocity | 0.06 | 0.38 | 1.75 ± 1.62 | 1.47 ± 1.16 |
| Time to max dilation velocity | 0.28 | 0.13 | 0.68 ± 0.38 | 0.79 ± 0.43 |
| Yellow | ||||
| Amplitude* | 0.62 | 0.58 | 1.87 ± 1.37 | 1.51 ± 1.16 |
| Latency* | 0.31 | 0.55 | 0.88 ± 0.62 | 0.71 ± 0.48 |
| Max constriction velocity | 0.63 | 0.68 | 1.35 ± 1.01 | 1.14 ± 0.76 |
| Time to max constriction velocity* | 0.21 | 0.38 | 0.70 ± 0.58 | 0.46 ± 0.43 |
| Max dilation velocity | 0.03 | 0.30 | 1.72 ± 1.59 | 1.57 ± 1.42 |
| Time to max dilation velocity | 0.29 | 0.03 | 0.61 ± 0.36 | 0.61 ± 0.37 |
SD, standard deviation.
The eye with greater within-eye asymmetry of each pupil metric was selected for each individual.
*
p-value<0.05 calculated with Student’s t-test.