Table 4.

Pupil response of each individual eye to various stimulation measured by pupillography in patients with glaucoma (N=148) and controls (N=71). All values expressed as Mean ± standard deviation.

	Amplitude (Ratio)		Latency (second)		Max Contraction Velocity (mm/ms)		Time to Max Contraction (second)		Max Dilation Velocity (mm/ms)		Time to Max Dilation (second)
	Glaucoma	Control	Glaucoma	Control	Glaucoma	Control	Glaucoma	Control	Glaucoma	Control	Glaucoma	Control
Full, bright
White	0.25 ± 0.05	0.29 ± 0.04	0.20 ± 0.03	0.18 ± 0.02	3.28 ± 0.79	3.81 ± 0. 74	0.42 ± 0.04	0.40 ± 0.03	2.02 ± 0.47	2.18 ± 0.43	1.20 ± 0.11	1.16 ± 0.09
Red	0.21 ± 0.05	0.25 ± 0.05	0.22 ± 0.03	0.20 ± 0.03	2.95 ± 0.74	3.39 ± 0.76	0.43 ± 0.04	0.41 ± 0.03	1.79 ± 0.42	2.03 ± 0.60	1.16 ± 0.11	1.10 ± 0.09
Green	0.24 ± 0.06	0.28 ± 0.05	0.21 ± 0.03	0.19 ± 0.03	3.19 ± 0.81	3.75 ± 0.78	0.42 ± 0.04	0.40 ± 0.03	1.95 ± 0.47	2.11 ± 0.41	1.18 ± 0.11	1.13 ± 0.09
Blue	0.22 ± 0.06	0.26 ± 0.05	0.22 ± 0.03	0.19 ± 0.03	3.10 ± 0.79	3.57 ± 0.78	0.43 ± 0.04	0.41 ± 0.04	1.86 ± 0.46	2.03 ± 0.40	1.17 ± 0.11	1.12 ± 0.09
Yellow	0.24 ± 0.06	0.29 ± 0.05	0.20 ± 0.03	0.18 ± 0.03	3.27 ± 0.83	3.80 ± 0.78	0.42 ± 0.04	0.40 ± 0.03	1.97 ± 0.51	2.18 ± 0.42	1.18 ± 0.11	1.14 ± 0.10
Peripheral, Bright
White	0.26 ± 0.06	0.31± 0.05	0.22 ± 0.03	0.19 ± 0.03	3.11 ± 0.81	3.69 ± 0.88	0.44 ± 0.05	0.41 ± 0.03	1.82 ± 0.49	2.12 ± 0.52	1.38 ± 0.12*	1.37 ± 0.09*
Red	0.19 ± 0.06	0.23 ± 0.05	0.23 ± 0.05	0.20 ± 0.03	2.53 ± 0.78	3.03 ± 0.75	0.45 ± 0.07	0.42 ± 0.04	1.64 ± 0.45	1.80 ± 0.41	1.29 ± 0.15*	1.26 ± 0.12*
Green	0.23 ± 0.06	0.28 ± 0.05	0.22 ± 0.04	0.19 ± 0.03	3.02 ± 0.84	3.55 ± 0.85	0.44 ± 0.05	0.41 ± 0.04	1.86 ± 0.51	2.02 ± 0.49	1.33 ± 0.12*	1.31 ± 0.10*
Blue	0.21 ± 0.06	0.26 ± 0.06	0.23 ± 0.03	0.20 ± 0.04	2.85 ± 0.80	3.43 ± 0.90	0.44 ± 0.05	0.41 ± 0.04	1.77 ± 0.48	1.94 ± 0.52	1.29 ± 0.13*	1.25 ± 0.13*
Yellow	0.24 ± 0.06	0.29 ± 0.05	0.22 ± 0.03	0.19 ± 0.03	3.08 ± 0.81	3.58 ± 0.82	0.44 ± 0.05	0.41 ± 0.04	1.90 ± 0.50	2.06 ± 0.45	1.32 ± 0.12*	1.32 ± 0.09*
Peripheral, Dim
White	0.24 ± 0.06	0.27 ± 0.05	0.23 ± 0.03	0.20 ± 0.03	2.87 ± 0.79	3.38 ± 0.89	0.45 ± 0.04	0.42 ± 0.04	1.77 ± 0.46	1.91 ± 0.41	1.37 ± 0.12*	1.36 ± 0.08*
Red	0.16 ± 0.05	0.19 ± 0.05	0.24 ± 0.04	0.22 ± 0.04	2.23 ± 0.65	2.61 ± 0.71	0.46 ± 0.05	0.43 ± 0.04	1.56 ± 0.45*	1.61 ± 0.35*	1.32 ± 0.12	1.28 ± 0.12
Green	0.21 ± 0.06	0.25 ± 0.06	0.23 ± 0.03	0.20 ± 0.03	2.73 ± 0.83	3.25 ± 0.79	0.45 ± 0.05	0.42 ± 0.04	1.76 ± 0.46*	1.88 ± 0.54*	1.33 ± 0.13	1.29 ± 0.09
Blue	0.19 ± 0.06	0.23 ± 0.06	0.24 ±0.04	0.21 ± 0.04	2.59 ± 0.79	3.06 ± 0.76	0.45 ± 0.05	0.42 ± 0.04	1.66 ± 0.47	1.82 ± 0.46	1.30 ± 0.14	1.26 ± 0.10
Yellow	0.22 ± 0.06	0.26 ± 0.05	0.23 ± 0.04	0.20 ± 0.03	2.85 ± 0.79	3.39 ± 0.85	0.44 ± 0.05	0.41 ± 0.04	1.82 ± 0.51*	1.95 ± 0.38*	1.32 ± 0.10*	1.29 ± 0.12*

The eye with smaller amplitude, slower velocities, and longer time to max contraction/dilation was selected for each individual.

Pupil metrics between glaucoma patients and normal subjects were compared using Student’s t test. All p-value<0.05 except those marked in *.