Kainic acid receptor (KAR) subunits colocalize with glial fibrillary acidic protein (GFAP)-positive astrocytes throughout the hippocampus and surrounding cortex following kainic acid (KA)-induced status epilepticus. (A-C) KAR subunit colocalization was routinely observed (but not quantified) throughout the hippocampus and surrounding cortex following KA-induced SE. Each panel are resulting colocalization analysis images demonstrating GluK4 colocalization in CA3 (A), GluK1 colocalization in the dentate gyrus (B), and GluK1 colocalization in the entorhinal cortex (C) following KA-induced SE. KAR subunit channel (green), GFAP channel (red), colocalized pixels (white). SP = stratum pyramidale, SR= stratum radiatum, GCL= granule cell layer. Scale bar = 50 µm.