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. Author manuscript; available in PMC: 2014 Jan 6.
Published in final edited form as: Nat Struct Mol Biol. 2012 Jan 22;19(2):10.1038/nsmb.2231. doi: 10.1038/nsmb.2231

Figure 2.

Figure 2

CBL autoinhibition via the E2-binding site. (a) Interactions in nCBL that stabilize the closed conformation. (b) Interactions in E2–CBL–S involved in CBL-E2 binding. (c) The LL2 conformations in nCBL (left), CBL–S (middle), and E2–CBL–S (right). All panels are colored as in Fig. 1.