Table 3.
Association of HPV L1 capsid protein expression with underlying histopathology according to multiplicity of HPV infection in HPV16-positive abnormal cervical cytology (N = 475).
| Histopathology | Histopathology | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤ CIN1 | ≥ CIN2 | ≤ CIN2 | ≥ CIN3 | |||||||||||||
| HPV* L1 | Number | (%) | HPV type | Number | (%) | Number | (%) | Number | (%) | p † | Number | (%) | Number | (%) | p † | |
| Negative | 287 | (60.4) | Single | 208 | (72.5) | 75 | (36.1) | 133 | (63.9) | 0.7663 | 98 | (47.1) | 110 | (52.9) | 0.0926 | |
| Multiple | 79 | (27.5) | 27 | (34.2) | 52 | (65.8) | 46 | (58.2) | 33 | (41.8) | ||||||
| Positive | 188 | (39.6) | Single | 152 | (80.9) | 123 | (80.9) | 29 | (19.1) | 0.1303 | 139 | (91.4) | 13 | (8.6) | 0.0004 | |
| Multiple | 36 | (19.1) | 25 | (69.4) | 11 | (30.6) | 25 | (69.4) | 11 | (30.6) | ||||||
*HPV: human papillomavirus
† Evaluated by χ2 test