Skip to main content
. 2013 Dec 16;11:41. doi: 10.1186/1477-3155-11-41

Table 5.

Description of experimental groups

Group Treatment Treatment abbreviation  
 Experimental design
Tumor ZnPcS 4 -AN Laser Doxorubicin
1
 Filtered water and no tumor implantation (negative control)
 NC
 -
 -
 -
 -
2
 Tumor inoculation and no treatment (control tumor)
 CT
 +
 -
 -
 -
3
 Intratumoral injection of 20 μL (0.5 mM) ZnPcS4-AN
 ZnPc
 +
 +
 -
 -
4
 Tumor irradiated only with light from a laser setup working at 670 nm, in a total dose of 100 J/cm2
 LS
 +
 -
 +
 -
5
 Intratumoral injection of 0.5 mM ZnPcS4-AN followed by light activation considering the same treatment as described for group 4
 PDT
 +
 +
 +
 -
6
 Intratumoral injection of 20 mg/m2 doxorubicin
 Dox
 +
 -
 -
 +
7
 Intratumoral injection of 0.5 mM ZnPcS4-AN and 20 mg/m2 Dox
 ZnPc/Dox
 +
 +
 -
 +
8
 Intratumoral injection of 20 mg/m2 Dox and the same treatment as group 4
 Dox/LS
 +
 -
 +
 +
9 Intratumoral injection of 0.5 mM ZnPcS4-AN and 20 mg/m2 Dox and the same treatment as group 5 Dox/PDT + + + +