Table 1.

Drugable driver mutations in non small cell lung cancer (modified from Kris, MG ea. ASCO 2011 and Hammerman P ea. WCLC 2011).

Adenocarcinoma
K-Ras	22 %
EGFR	17 %
EML4-ALK	7 %
B-Raf	2 %
Other	6%
No driver mutation detected	46 %
Squamous cell lung cancer
FGFR1 amplification	20 - 25 %
FGFR2 mutation	5 %
PIK3CA mutation	9 %
PTEN mutation/deletion	18 %
DDR2 mutation	4 %