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. Author manuscript; available in PMC: 2014 Jan 6.
Published in final edited form as: Curr Opin Immunol. 2011 Jan 14;23(1):10.1016/j.coi.2010.12.015. doi: 10.1016/j.coi.2010.12.015

Figure 4.

Figure 4

AIM2-dependent signaling and the inflammatory responses: Cytosolic DNA binds to the HIN-200 domains of AIM2 and activates the ASC/Caspase1 inflammasome pathway to produce IL-1β.