Table 1.
Summary of SCD Right Heart Catheterization Studies
Hemodynamic values from right heart catheterization studies in SCD.
First Author (Ref.#) | Number of Subjects Screened | Exclusions | Criteria for RHC | Number of RHCs | Number of Subjects with PH* | % of RHC with PH | % of Screened Subjects with PH | Mean Age of PH Subjects | mPAP (mmHg) | PVR (dyne* sec/cm5) | CO (Liters/min) | 6MWD (m) | Duration of Follow-up (yrs) | Mortality in PH group |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mehari et al.(100) | 533 | none | TRV ≥2.8m/s 6MWD < 500m unexplained dyspnea or desaturation | 86 | 56 | 65 | 11 | 41 | 36 ± 9 | 229 ± 149 | 8 ± 3 | 358 ± 113 | 4.4 | 36% |
Parent et al. (85) | 445 | renal insufficiency restrictive lung disease liver disease | TRV ≥ 2.5m/s | 96 | 24 | 25 | 5 | 45 | 30 ± 6 | 138 ± 58 | 9 ± 2 | 404 ± 94 | 2.2 | 13% |
Fonseca et al (84) | 80 | none | TRV ≥ 2.5m/s | 26 | 8 | 31 | 10 | 46 | 33 ± 9 | 179 ± 120§ | 5 ± 2£ | 460 ± 152 | 2.8¤ | 38% |
Pulmonary hypertension defined as mean PAP≥25mmHg
Median (interquartile range)
converted mean value: PVR measured in Woods units as 2.24 ±1.5
Cardiac index (L/min/m2)
Estimated from figure in epub