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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: J Allergy Clin Immunol. 2013 Nov 1;132(6):10.1016/j.jaci.2013.08.045. doi: 10.1016/j.jaci.2013.08.045

FIG. 3.

FIG. 3

Reduced mast cell degranulation in STAT3-mutant mice. A, IgE-mediated systemic anaphylaxis in mut-Stat3 mice compared with wild-type littermate controls. Data are representative of 2 independent experiments with 4 to 5 mice per group. B, Compound 48/80 was used to induce IgE-independent anaphylaxis in mut-Stat3 and wild-type mice. Data are representative of 4 mice per group. C, Dot plot of surface FcεRI expression versus CD117 expression. D, Percentage of Lin−IgE+FcεRI+CD117+ peritoneal mast cells. Data are cumulative of 2 independent experiments of age- and sex-matched animals with 4 to 6 mice per group.