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Pre-chemoradiation therapy (CRT) DW-MRI (left) shows a 4.8 cc, polypoid rectal tumor with very high signal intensity (arrow). Post-CRT DW-MRI (right) shows a significant decrease in tumor volume (1 cc). Residual tumor with intermediate signal intensity limited to the mucosa and submucosa can be seen (arrow). Courtesy of Engin, et al. 63
