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Top: fluorescence images of cultured astrocytes transfected with liposomes, showing red fluorescence due the rhodamine content of liposomes. Liposomes do not penetrate cell nuclei (blue Hoechst staining). Bottom: MR T2-weighted images (left) and R1 (=1/T1) parametric maps of a rat brain 24 hours after intra-parenchymal injection of liposomes. The presence of gadolinium in liposomes enables their detection as hypointense areas on T2w images and hyperintense regions on R1 maps.
