Table 1.
Allele and genotype frequency of IL-10 polymorphisms
| Position of IL-10 polymorphisms | Controls Total=177 n (%) |
Carriers Total=80 n (%) |
HAM/TSP Total =75 n (%) |
|---|---|---|---|
| IL-10 -1082*G/A | |||
| Allele G A |
121 (34.2) 233 (65.8) |
49 (30.6) 111 (69.4) |
47 (31.3) 103 (68.7) |
| Genotype | |||
| GG AG AA |
15 (8.5) 91 (51.4) 71 (40.1) |
5 (6.2) 39 (48.8) 36 (45.0) |
8 (10.7) 31 (41.3) 36 (48.0) |
| IL-10 –819*C/T | |||
| Allele C T |
259 (73.2) 95 (26.8) |
101 (63.1) 59 (36.9)a |
93 (62.0) 57 (38.0)b |
| Genotype | |||
| CC CT TT |
95 (53.7) 69 (39.0) 13 (7.3) |
34 (42.2) 33 (41.2) 13 (16.3)c |
28 (37.3) 37 (49.3) 10 (13.4)d |
| IL-10 -592*C/A | |||
| Allele C A |
259 (73.2) 95 (26.8) |
101 (63.1) 59 (36.9)a |
93 (62.0) 57 (38.0)b |
| Genotype | |||
| CC AC AA |
95 (53.7) 69 (39.0) 13 (7. 3) |
34 (42.2) 33 (41.2) 13 (16.3)c |
28 (37.3) 37 (49.3) 10 (13.4)d |
a P =0.02 vs. controls
b P =0.01 vs. controls.
c P =0.04 vs. controls.
d P =0.04 vs. controls.