Table 2.
Distribution of IL-10 haplotypes in healthy controls, HAM/TSP patients and HTLV-I carriers
| IL-10 haplotype | Controls total=354 n (%) |
Carriers total=160 n (%) |
HAM/TSP total=150 n (%) |
HAM/TSPH and Carriers (total=310) n (%) |
|---|---|---|---|---|
| GCC | 120 (33.9) | 49 (30.6) | 45 (30.0) | 94 (30.3) |
| ACC | 139 (39.3) | 52 (32.5) | 49 (32.7) | 101 (32.6) |
| ATA* | 95 (26.8) | 59 (36.9) | 56 (37.3) | 115 (37.1) |
*Significant differences were observed between HAM/TSP patients and healthy controls (P=0.02, OR; 1.62, 95% CI: 1.05-2.48), HTLV-I carriers and healthy controls (P=0.02, OR; 1.59, 95% CI: 1.04-2.41), and HTLV-I infected individuals with controls (P=0.005, OR; 1.60, 95% CI: 1.14-2.26).