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. Author manuscript; available in PMC: 2014 Jan 6.
Published in final edited form as: J Med Chem. 2013 Nov 1;56(21):10.1021/jm401002r. doi: 10.1021/jm401002r

Table 2.

The effect of linker length on LSD1 inhibition.

graphic file with name nihms-539339-t0021.jpg
Comp. n R IC50(μM)
41 0 p-CH3 >125
42 0 p-OCH3 >125
43 0 o-F >125
44 0 m-CF3 >125
45 2 p-CH3 >125
46 2 p-F >125