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. 2013 Dec 28;10:157. doi: 10.1186/1742-2094-10-157

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Copyright © 2013 Sun et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Schematic representation of the analyzed area induced by subarachnoid hemorrhage (SAH). (A) control group and (B) SAH group. C and D: The time course of cerebral blood flow (CBF) and mean arterial blood pressure (MABP) in control group (n = 18), SAH group (n = 18), SAH + vehicle group (n = 18), and SAH + tamoxifen group (n = 18). (C) Graphs of CBF in middle cerebral artery (MCA) area measured by continuous laser Doppler flowmeter over the left hemisphere. (D) Secondary to injection of saline or blood, MABP increased sharply in all four groups. *P <0.05 and **P <0.01 between control animals versus SAH animals.