Table 1.

Clinical features of RE patients

	Patient 1	Patient 2	Patient 3	Patient 4
Age of onset, gender	3 years, female	8 years, female	14 years, male	12 years, female
Seizure type	CPS, Gen, right face/hand EPC	CPS, right face/hand EPC	CPS, right face/hand EPC	CPS, right face/hand EPC
Hemisphere	Left	Left	Bilateral	Left
Neurologic deficit(s)	Right hemiparesis	Right hemiparesis	Right hemiparesis, aphasia	Right hemiparesis
Neuroimaging	Cortical and white matter signal	Cortical and white matter signal	Cortical and white matter signal	Cortical and white matter signal
Surgery, age	Left hemispherectomy, 4 years	Left hemispherectomy, 11 years	SPT, 17 years; left face/hand area resection, 17 years	Left face/hand area resection, 18 years
Neuropathology	Mononuclear cell infiltration with gliosis	Mononuclear cell infiltration with gliosis	Mononuclear cell infiltration with gliosis	Mononuclear cell infiltration with gliosis
Clinical outcome	Engel class I, seizure-free (at 14 months)	Engel class I, seizure-free (at 24 months)	Engel class IV, death	Engel class III, 2 years (lost to follow-up)
Treatment(s)	GCs, no benefit	GCs, good response	GCs, IVIg, tacrolimus, cyclophosphamide (50 mg/kg)	GCs, IVIg, methotrexate, no benefit

CPS, complex partial seizure; EPC, epilepsia partialis continua; GCs, glucocorticoids; Gen, generalized seizures; IVIg, intravenous immune globulin; RE, Rasmussen’s encephalitis; SPT, subpial transaction.