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. Author manuscript; available in PMC: 2014 Oct 21.
Published in final edited form as: J Mater Chem B. 2013 Jun 10;1(39):10.1039/C3TB20595A. doi: 10.1039/C3TB20595A

Figure 7. In vivo integrity of BASP.

Figure 7

Mice bearing EF43.fgf4 mammary xenografts were injected intravenously with BASP. After a 4h circulation time, the animals were sacrificed and the tumor and liver were harvested and processed for histological analysis. (A) Fluorescence microscopy and (B) Immunohistochemistry analyses for bacteriophage (brown) show that the (i) bacteriophage remains associated with S1MP and the assembly is not impaired in the circulation (ii) Negative staining control; (C) Hyperspectral images of the liver show superimposed spectral mapping of silicon and AuNP also confirming the close association of the AuNP and S1MP in the BASP.