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Control group (saline). A – At 7 days, there is an aggressive inflammatory response. The granulation tissue is thick and presents macrophages and lymphocytes. Fibroblasts are near the collagen fibers in a disorganized distribution. Blood vessels are distributed all over the tissue. B - At 28 days, the fibrous tissue present well organized collagen fibers parallel to implant. There are a few inflammatory cells and capillaries. HE – Original magnification=40x
