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. Author manuscript; available in PMC: 2014 Nov 4.
Published in final edited form as: Vaccine. 2013 Sep 19;31(46):10.1016/j.vaccine.2013.09.003. doi: 10.1016/j.vaccine.2013.09.003

Fig. 3.

Fig. 3

Epitope-specific IgG and sIgA antibody responses in mice after oral immunization with BPV-gp41 CVLPs. Mice (3-5 per group) were orally immunized 3 times at two-week intervals with 10ug of 2-1 or L1-MPER CVLPs. PBS or BPV VLPs orally immunized mice were control groups. Two weeks after the final boost, sera and fecal extracts were collected. Peptide ELISAs were performed to analyze 2F5 and 4E10 peptide reactivity of sera and fecal extracts. (A) 2F5 or 4E10 epitope-specific IgG titer in serum. (B) 2F5 or 4E10 epitope-specific secretory IgA (sIgA) titer in fecal extracts. Data are shown as geometrical mean ± s.e.m and are representative of two independent experiments.