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Antiproliferative effects of the eight compounds on human colorectal cancer cells. HCT-116 (A) and SW-480 (B) cells were treated with compounds at concentrations of 3, 10, 30, and 50 μM for 48 h. Results are expressed as percent of control (solvent vehicle set at 100%). Data are presented as mean ± SD of triplicate experiments. *P<0.05, **P<0.01 compared with control. (C). IC50 of compounds 1–8 on HCT-116 and SW-480 cells.
