Table I.
Arteriolar diameters and spontaneous vasomotor tone
| β1e3/e3 | ismβ1e3/e3 | |||||
|---|---|---|---|---|---|---|
| 1A | 2A | 3A | 1A | 2A | 3A | |
| Diameter, µm | ||||||
| Rest | 59 ± 5 | 14 ± 2 | 6 ± 1 | 44 ± 1* | 11 ± 1 | 7 ± 1 |
| Maximum | 61 ± 5 | 32 ± 3 | 22 ± 3 | 45 ± 2* | 19 ± 3* | 12 ± 2* |
| Vasomotor tone | 5 ± 1 | 57 ± 6 | 68 ± 4 | 3 ± 1 | 35 ± 9* | 36 ± 6* |
Arteriolar diameters and spontaneous vasomotor tone in cremaster muscle preparations of β1e3/e3 and ismβ1e3/e3 mice. Maximum diameters were recorded during superfusion with ACh + SNP (10 µM each). Vasomotor tone is expressed as “% maximum diameter” calculated as: [(maximum diameter - resting baseline diameter)/maximum diameter] × 100. Values are means ± SE (n=6 per cell).
Arteriolar diameter of ismβ1e3/e3 significantly different from corresponding branch of β1e3/e3, P < 0.01.