Table 5.
Model 1 | Model 2a) | Model 3b) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
N | B | 95 % CI | B | 95 % CI | B | 95 % CI | ||||
Week 13 to 17 | ||||||||||
Other supplements only | 634 | .922 | .14 | 1.69 | 0.335 | -0.45 | 1.12 | -.246 | -1.08 | 0.59 |
Folic acid only | 211 | 7.549 | 6.37 | 8.71 | 6.879 | 5.69 | 8.06 | 6.744 | 5.52 | 7.96 |
Folic acid plus | 947 | 7.425 | 6.73 | 8.11 | 6.657 | 5.94 | 7.36 | 5.580 | 4.76 | 6.39 |
| ||||||||||
Week 9 to 12 | ||||||||||
Other supplements only | 234 | 0.015 | -1.16 | 1.10 | -0.115 | -1.30 | 1.07 | -1.209 | -2.43 | 0.01 |
Folic acid only | 512 | 1.348 | .47 | 2.22 | 0.805 | -0.08 | 1.69 | -0.405 | -1.34 | 0.53 |
Folic acid plus | 942 | 4.459 | 3.74 | 5.17 | 3.686 | 2.93 | 4.43 | 0.238 | -0.77 | 1.24 |
| ||||||||||
Week -4 to 8 | ||||||||||
Other supplements only | 267 | 2.772 | 1.65 | 3.89 | 2.491 | 1.36 | 3.61 | 2.309 | 1.15 | 3.45 |
Folic acid only | 526 | 2.975 | 2.11 | 3.84 | 2.406 | 1.52 | 3.28 | 1.556 | 0.62 | 2.48 |
Folic acid plus | 938 | 5.006 | 4.28 | 5.72 | 4.294 | 3.54 | 5.03 | 2.291 | 1.33 | 3.25 |
Supplement use pattern are included as dummies. Linear regression was used to determine the coefficients for folate plasma levels (subjects with no supplement use in the relevant period as reference, B=0). Missing was excluded pairwise.
Adjusted for education, age, planned pregnancy, BMI and smoking.
Adjusted for education, age, planned pregnancy, BMI, smoking, and the other windows of supplement use (w 9-12 and w -4-8; w 13-17 and w -4-8; w 13-17 and w 9-12).