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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Mol Nutr Food Res. 2012 Oct 15;57(4):10.1002/mnfr.201200116. doi: 10.1002/mnfr.201200116

Table 5.

Crude and adjusted linear coefficients for maternal report of supplement use and plasma levels of folate, no supplement use as reference, N=2911.

Model 1 Model 2a) Model 3b)
N B 95 % CI B 95 % CI B 95 % CI
Week 13 to 17
Other supplements only 634 .922 .14 1.69 0.335 -0.45 1.12 -.246 -1.08 0.59
Folic acid only 211 7.549 6.37 8.71 6.879 5.69 8.06 6.744 5.52 7.96
Folic acid plus 947 7.425 6.73 8.11 6.657 5.94 7.36 5.580 4.76 6.39

Week 9 to 12
Other supplements only 234 0.015 -1.16 1.10 -0.115 -1.30 1.07 -1.209 -2.43 0.01
Folic acid only 512 1.348 .47 2.22 0.805 -0.08 1.69 -0.405 -1.34 0.53
Folic acid plus 942 4.459 3.74 5.17 3.686 2.93 4.43 0.238 -0.77 1.24

Week -4 to 8
Other supplements only 267 2.772 1.65 3.89 2.491 1.36 3.61 2.309 1.15 3.45
Folic acid only 526 2.975 2.11 3.84 2.406 1.52 3.28 1.556 0.62 2.48
Folic acid plus 938 5.006 4.28 5.72 4.294 3.54 5.03 2.291 1.33 3.25

Supplement use pattern are included as dummies. Linear regression was used to determine the coefficients for folate plasma levels (subjects with no supplement use in the relevant period as reference, B=0). Missing was excluded pairwise.

a)

Adjusted for education, age, planned pregnancy, BMI and smoking.

b)

Adjusted for education, age, planned pregnancy, BMI, smoking, and the other windows of supplement use (w 9-12 and w -4-8; w 13-17 and w -4-8; w 13-17 and w 9-12).