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. 2013 Dec 28;8:296. doi: 10.1186/1748-717X-8-296

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Copyright © 2013 Summerer et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Sensitivity of primary HNSCC cell cultures to 5-FU treatment and ionizing radiation. Cell viability (XTT-assay) of HN1957 (a) and HN2092 (b) 48 h after 5-FU treatment relative to DMSO-controls. Each data point represents the mean of three biological replicates. Dashed lines mark the 5-FU concentrations selected for in vitro radiochemotherapy modeling. Survival curves were generated by colony forming assay for HN1957 (c) 6 days after irradiation and HN2092 (d) 12 days after irradiation. Error bars represent the standard deviation of three biological replicates.