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. Author manuscript; available in PMC: 2014 Nov 12.
Published in final edited form as: Biochemistry. 2013 Nov 1;52(45):10.1021/bi400926k. doi: 10.1021/bi400926k

FIGURE 8.

FIGURE 8

Comparison of pH-dependent membrane insertion of the hydrophobic helical hairpins of the T-domain and Bcl-xL. A) The membrane insertion of the T-domain into LUV, determined as a function of the pH, strongly depends on the mole fraction of POPG in the LUV (only fitting curves from reference (13) are shown). B) The membrane insertion of Bcl-xL, studied as a function of the pH by following the changes in emission intensity at 525 nm, does not strongly depend on the POPG content of LUV (data in 90PC/10PG is omitted since there is no initial binding of the protein to LUV with this lipid composition). The data was fitted to a two-state model as described in methods.