Table 1.

Trio type, parental mating type, case type, and pseudo controls for case-parents data.

Trio type	Parental mating type	Case type	Pseudo controls
12	1: AA x AA	2: AA	AA, AA, AA
22	2: AA x Aa	2: AA	Aa, AA, Aa
21		1: Aa	AA, AA, Aa
31	3: AA x aa	1: Aa	Aa, Aa, Aa
42	4: Aa x Aa	2: AA	aa, Aa, Aa
41		1: Aa	Aa, AA, aa
40		0: aa	AA, Aa, Aa
51	5: Aa x aa	1: Aa	aa, Aa, aa
50		0: aa	Aa, Aa, aa
60	6: aa x aa	0: aa	aa, aa, aa

The first column shows the trio types, which are determined by parental mating types and case genotype. The second column shows the parental mating types, and if we ignore the order of parents there are 6 types in total, as shown from top to bottom. The third column shows the genotypes of the affected offspring; there are three types in total, AA, Aa and aa, which are represented by type 2, 1, and 0, respectively. The fourth column shows the genotypes of the pseudo siblings of the affected offspring under the 1:3 matching; the genotype in bold letters is that of the pseudo sibling of the affected offspring under the 1:1 matching.