Table 1. Participant characteristics.
Characteristic | Lean | Obese | T2D |
---|---|---|---|
Age (years) | 39±4 | 46±4 | 48±3 |
Sex (male/female) | 4/4 | 4/4 | 3/5 |
BMI (kg/m2) | 24±0.9 | 28±1* | 34±2*** |
Weight (kg) | 74±5 | 81 ±5 | 98±5*** |
Fasting glucose (mmol/l) | 5.22±0.09 | 5.46±0.14 | 6.83±0.43** |
Fasting insulin (pmol/l) | 41 ±9 | 121 ±23 | 79±18 |
Basal glucose production (mg m−2 min−1) | 80.8±6.7 | 74.2±6.3 | 80.3±4.0 |
Insulin-stimulated glucose disposal (mg m−2 min−1) | 465.3±90.1 | 282.5±20.8 | 233.4±23.2 |
Data are given as means ± SEM
Glucose disposal rates were calculated as the average value during the final 30 min of insulin infusion
p≤0.05,
p≤0.01,
p≤0.001 (ANOVA) T2D, type 2 diabetes