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. 2014 Jan 6;9(1):e84788. doi: 10.1371/journal.pone.0084788

Table 2. Pleural fluid and microbiology characteristics (first thoracentesis).

Total (n = 79) Success (n = 64) Failure (n = 15) p
Pleural fluid analysis
Frank pus (empyema), n (%) 52 (66%) 39 (61%) 13 (87%) 0.073
Protein, g/L (IQR)(†) 46 (41–50) 45 (41–50) 47 (34–48) 0.534
LDH, IU/L (IQR)(†) 4336 (1721–17810) 3932 (1134–14872) 17284 (9452–26068) 0.079
pH (IQR)(†) 7.19 (7.0–7.5) 7.10 (7.0–7.5) 7.50 (7.15–7.75) 0.422
Glucose level, mmol/L (IQR)(†) 1.0 (0.1–3.8) 1.0 (0.1–4.1) 0.6 (0.1–1.1) 0.716
Micro-organisms observed on Gram staining, n (%) 41 (52%) 28 (44%) 13 (87%) 0.003
Positive culture, n (%) 36 (46%) 26 (41%) 10 (67%) 0.088
Positive culture on aerobic atmosphere, n (%) 25 (32%) 20 (31%) 5 (36%) 0.759
Positive culture on anaerobic atmosphere, n (%) 16 (20%) 11 (17%) 5 (36%) 0.036
Polymicrobial culture, n (%) 12 (15%) 8 (12.5%) 4 (27%) 0.227
Microbiological characteristics
Positive blood culture, n (%) 7 (9%) 5 (8%) 2 (14%) 0.612
Positive pneumococcal urine antigen, n (%) 7 (37%) 5 (38.5%) 2 (33%) 1.000
Identified bacteria
Anaerobic bacteria, n (%) 16 (20%) 11 (17%) 5 (33%) 0.171
Streptococcus milleri, n (%) 15 (19%) 12 (19%) 3 (20%) 1.000
Streptococcus pneumoniae, n (%) 12 (15%) 9 (14%) 3 (20%) 0.689
Other Streptococcus sp., n (%) 8 (10%) 5 (8%) 3 (20%) 0.171
Staphylococcus aureus, n (%) 3 (4%) 2 (3%) 1 (7%) 0.473
Gram-negative bacteria, n (%) 3 (4%) 2 (3%) 1 (7%) 0.473

Quantitative variables are indicated as median (IQR), qualitative variables are indicated as numbers (%). (†) Variables with >10% of missing data.