Figure 4. Effects of iron overload on BBB breakdown and apoptosis.
Each panel represented the expression of tight junctions protein; occludin (A), apoptotic-protein; Bax (B) and anti-apoptotic protein; Bcl-2 (C) and Bax/Bcl-2 ratio (D). *P<0.05 vs. Normal diet groups; † P<0.05 vs. HFe4w. ND: normal diet fed groups; HFe: high-iron diet fed groups.