Figure 5. Effects of the pharmacological interventions by deferiprone and n-acetyl cysteine on learning and memory behavior.

Each panel represented locomotors activity (A) and learning and memory behavior indicated by time to reach platform (B, D and F) and time spent in target quadrant (C and E). *P<0.05 vs. Normal diet treated with vehicle (NDV); ^† P<0.05 vs. HFe treated with vehicle (HFeV); ^‡ P<0.05 vs. HFe treated with either L1 or NAC (HFeL1 or HFeNAC). ND: normal diet fed groups; HFe: high-iron diet fed groups; L1: deferiprone; NAC: n-acetyl cysteine.