Table 1. Effects of 4-, and 8-week high iron diet consumption on body weight, plasma NTBI, plasma MDA, brain MDA and brain iron level in rats.
Parameters | ND4w | HFe4w | ND8w | HFe8w |
Body weight (g) | 317.00±3.74 | 260.83±3.75* | 395.00±8.37 | 305.71±10.99* † |
Plasma NTBI (µM) | 0 | 2.51±0.118* | 0 | 3.35±0.141* † |
Plasma MDA (µM) | 6.42±2.58 | 23.36±1.72* | 10.30±3.46 | 31.31±3.90* † |
Brain MDA (µM/mg protein) | 0.83±0.04 | 1.25±0.04* | 1.02±0.10 | 1.50±0.07* † |
Brain iron (µM/mg protein) | 7.45±0.13 | 9.62±0.28* | 7.55±0.16 | 12.91±1.27* † |
p<0.05 vs. Normal diet-fed rats,
p<0.05 vs. High iron diet-fed rats for 4 weeks. ND; normal diet-fed rats, HFe; high iron diet-fed rats, 4w; 4-week diet consumption, 8w; 8-week diet consumption, NTBI; non-transferrin bound iron, MDA; malondialdehyde.