Table 3.
Bivariate Association of Comorbidity Burden With Guideline Concordance for Stage I - III Colorectal Cancer Patients Living in Appalachian Counties in 4 States, 2006- 2008
| Comorbidity Burden | Chemotherapy for stage III colon cancer (n=561) |
›12 lymph nodes harvested stages I – III colon cancer (n=2932) |
Radiation therapy for Stage III rectal cancer (n=184) |
|||
|---|---|---|---|---|---|---|
|
| ||||||
| N | %yes | N | %yes | N | %yes | |
|
| ||||||
| Total | 561 | 62.9 | 2932 | 66.3 | 184 | 56.0 |
| Comorbidity Severity | ||||||
| none | 72 | 65.3a | 350 | 69.7 | 37 | 64.9 |
| mild | 247 | 70.0 | 1208 | 66.0 | 92 | 52.2 |
| moderate | 79 | 60.8 | 507 | 67.9 | 19 | 52.6 |
| Severe | 163 | 52.1 | 867 | 64.6 | 36 | 58.3 |
|
| ||||||
| Comorbidities | ||||||
| AMI | 40 | 45.0a | 193 | 62.2 | 8 | 25.0 |
| CAD | 34 | 58.8 | 163 | 63.8 | 6 | 66.7 |
| CHF | 67 | 44.8a | 442 | 63.1 | 15 | 46.7 |
| Arrhythmia | 68 | 57.4 | 514 | 66.1 | 18 | 50.0 |
| Hypertension | 396 | 63.6 | 2114 | 66.0 | 120 | 52.5 |
| Venous Disease | 14 | 64.3 | 66 | 63.6 | 2 | 50.0 |
| PAD | 16 | 62.5 | 81 | 60.5 | 1 | 100.0 |
| Respiratory diseases | 132 | 52.2a | 823 | 64.6 | 45 | 44.4 |
| Hepatic | 8 | 37.5 | 37 | 70.3 | 2 | 100.0 |
| Stomach or Intestine | 41 | 58.5 | 281 | 68.0 | 15 | 60.0 |
| Pancreas | 1 | 100.0 | 8 | 62.5 | 0 | -- |
| Renal System | 27 | 55.5 | 180 | 60.0 | 7 | 28.6 |
| Diabetes | 189 | 61.9 | 883 | 62.5a | 51 | 58.8 |
| Stroke or CVA | 4 | 25.0 | 65 | 58.5 | 3 | 33.3 |
| Dementia | 8 | 12.5a | 63 | 60.3 | 2 | 0.0 |
| Paralysis | 1 | 0.0 | 24 | 70.8 | 0 | -- |
| Neuromuscular | 12 | 50.0 | 103 | 62.1 | 2 | 50.0 |
| Psychiatric | 1 | 0.0 | 7 | 71.4 | 0 | -- |
| Rheumatologic | 3 | 66.6 | 10 | 50.0 | 0 | -- |
| AIDS | 0 | -- | 0 | -- | 0 | -- |
| Solid Tumor | 145 | 66.9 | 565 | 66.7 | 24 | 41.7 |
| Leukemia | 10 | 60.0 | 33 | 66.7 | 0 | -- |
| Lymphoma | 0 | -- | 1 | 0.0 | 0 | -- |
| Alcohol Abuse | 4 | 25.0 | 11 | 54.5 | 1 | 100.0 |
| Illicit Drugs | 0 | -- | 0 | -- | 0 | -- |
| Obesity | 12 | 58.3 | 32 | 81.3 | 2 | 50.0 |
|
| ||||||
| Multimorbidity Count | ||||||
| 0 morbidities | 72 | 65.3 | 350 | 69.7 | 37 | 64.9 |
| 1 comorbidity | 155 | 69.7 | 742 | 66.8 | 56 | 55.4 |
| 2-3 comorbidities | 223 | 61.0 | 1221 | 66.4 | 70 | 55.7 |
| 4-5 comorbidities | 86 | 57.0 | 464 | 65.7 | 17 | 52.9 |
| 6+ comorbidities | 25 | 52.0 | 155 | 57.4 | 4 | 0.0 |
a
Chi-square, P < .05 for colon cancer resection.