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gAPN decreased IKK-IκB-NF-κB signaling activation in MI/R myocardium, which was blocked by PKA deficiency. A: phosphorylated IKK expression, representative Western blots shown (n = −6 hearts/group). B: phosphorylated IκB expression, representative Western blots shown (n = 5–6 hearts/group). C: activated NF-κB, determined by ELISA (n = 6–8 hearts/group). *P < 0.05, **P < 0.01 vs. vehicle; #P < 0.05, ##P < 0.01 vs. Scramble with the same treatment.
