Table 3.
Effects of tocopherol isoforms on modulation of gene transcription in non-IFNγ-PMA-challenged FHs 74 Int cells
Fold Regulation |
||||
---|---|---|---|---|
Gene | Control | + α-Toc | + γ-Toc | + δ-Toc |
4 h | ||||
IL8 | 1.0a | 3.0b | 1.6a | 1.8a |
24 h | ||||
GSTA1 | 1.0a | 1.1a | −1.1a | −10.6b |
GCLC | 1.0a | 1.1a | −1.5b | −6.4c |
IL8 | 1.0a | 1.3a | 21.5b | 28.6c |
PTGS2 | 1.0a | 2.2a | 9.4a | 147.8b |
Fold regulation is expressed relative to untreated control cells. Control group consists of untreated cells. Only genes that were significantly regulated >3-fold are listed. Different letters indicate significant (P < 0.05) differences between treatment groups.