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Apical localization of Cav2 (red) in renal CD PCs of rats treated with DDAVP for 2 wk. Similar to Cav1, Cav2 assumed a largely apical localization in IMCD PCs (arrows) of 2-wk DDAVP-treated SD (A), LE (B), and BB (not shown) rats. A similar Cav2 subcellular localization was found in PCs of the ISCD (arrows) in SD (C), LE (D), and BB rats. Insets show higher-magnification images of cells, demonstrating examples of apical Cav2 staining (arrows). Bars = 20 μm; bars in insets = 5 μm.
