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Time-dependent urine osmolality increase after vasopressin (DDAVP) treatment of BB rats (1.2 μg/day via osmotic pumps). Urine osmolality was significantly increased at 24 h postimplantation of the pumps, peaked after 7 days, and was maintained at these elevated levels for the 3-wk duration of the treatment. Values are shown as means ± SE.
