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. 2013 Oct 16;305(12):F1783–F1795. doi: 10.1152/ajprenal.00622.2012

Fig. 3.

Fig. 3.

Subcellular localization of aquaporin-2 (AQP2; red) in control and DDAVP-treated BB rats. AQP2 had a diffuse localization in inner medullary CD (IMCD) PCs of control BB rats (A), which became polarized to the apical membrane of these cells after treatment with DDAVP for 3 days (B) or 2 wk (C). Similarly, ISCD PCs exhibited cytosolic diffuse AQP2 in control animals (D) but sharp apical AQP2 localization after 3 days (E) or 2 wk (F) of DDAVP treatment. Bars = 25 μm.